Introduction
Did you know that around 1 in 10 medical claims in the U.S. are denied, according to the American Medical Association? For healthcare providers and billing teams, managing these denied claims can be overwhelming. A major challenge arises from the Explanation of Benefits (EOBs), which are documents from insurers that outline payments, adjustments, and denials.
One of the most confusing elements of an EOB is the denial code. These short codes, such as CO 45, CO-11, CO 50, and PR 227, reveal why a claim was rejected. Understanding these codes often requires hours of research, switching between documents and payer portals, and navigating multiple systems. For example, CO-50 simply indicates that the procedure wasn’t deemed medically necessary.
AI is now transforming this workflow. With its ability to instantly read and interpret denial codes, AI enables healthcare teams to process EOBs more efficiently, accurately, and with reduced stress. In this blog, we’ll explore how AI is streamlining claims management and saving valuable time.

The Importance of EOB Statements in Healthcare Revenue Cycle
An Explanation of Benefits (EOB) contains a wealth of information, including patient details, procedure codes, payments, adjustments, and more. However, tucked within all this data are denial codes, which are the key to understanding why specific claims were rejected. The problem? They’re often buried deep in the document and difficult to decode.
Take the denial code “CO-97” as an example. A billing team member has to:
- Locate the code hidden within tables or mixed among other details.
- Cross-check it with a denial code list or the payer’s website.
- Discover it means: “The benefit for this service is included in the payment/allowance for another service/procedure that has already been adjudicated.”
- Finally, decide whether to appeal, correct the claim, or write it off.
This repetitive, manual cycle, multiplied across hundreds of claims every month, becomes overwhelming. With different insurers using different formats and staff interpreting codes in their own ways, the results are inconsistent.
The lack of a standardized process often leads to rework, missed appeal deadlines, or delayed payments. Add in the challenges of training new hires or managing staff turnover, and clearly, the traditional approach is due for an upgrade.
AI to the Rescue: Turning EOB Chaos into Clarity
For healthcare providers, Explanation of Benefits (EOBs) are a daily reality, but one that is often filled with frustration. Buried within pages of payer details, denial codes appear as small snippets of text that carry enormous consequences. Each one signals a rejected claim, lost revenue, and more work for your billing team. Decoding them manually means flipping through payer references, cross-checking lists, or searching online – a time-consuming, error-prone, and draining process for staff.
AI changes this story. With advanced technologies like Optical Character Recognition (OCR) and Natural Language Processing (NLP), AI transforms chaotic EOB data into clear, organized information within seconds.
How AI Processes Denial Codes (Step-by-Step)
- Step 1: Digitization – OCR reads digital or scanned EOBs, capturing all text, including handwritten notes.
- Step 2: Identification – NLP pinpoints denial codes, such as PR-204 or CO-16, hidden among other details.
- Step 3: Decoding – AI instantly maps these codes to their correct meanings using an updated denial code database.
- Step 4: Simplification – Each code is explained in plain English; e.g., “The patient’s current plan doesn’t cover this service.”
- Step 5: Actionable Insights – Teams can immediately take the right step: appeal, resubmit, or update insurance details.
Instead of manually cross-checking references or googling codes, your team immediately knows the issue and how to resolve it. Whether it’s an appeal, a correction, or an update, the next step is clear and actionable, leaving no room for doubt or delay.
The biggest advantage? Speed and accuracy. AI completes this entire process in seconds, ensuring your staff isn’t wasting valuable hours manually untangling codes. Instead of confusion, your team gets instant clarity.
AI isn’t just the future of denial management; it’s the fix your billing team needs today.

AI-Powered Denial Code Decoding: Benefits You Can’t Ignore
Switching from manual denial code processing to an AI-powered system isn’t just about saving time; it completely transforms how healthcare organizations handle claims. Here’s how:
1. Speed
Manually locating and interpreting denial codes can take 10–15 minutes per claim. Multiply that by hundreds of claims a day, and the time drain becomes obvious. AI changes the equation by scanning an uploaded EOB, extracting every denial code, and explaining it in seconds. What used to take hours now happens almost instantly, freeing up staff for higher-value tasks.
2. Clarity
Denial codes, such as “CO-109,” are often cryptic unless you’re a billing expert. In reality, it means “Claim not covered due to missing documentation.” AI eliminates the guesswork by converting code into clear, plain-English explanations. Your team doesn’t waste time decoding jargon; they get the information they need to act quickly.
3. Consistency
EOB formats vary wildly across payers. Some are neatly structured, while others bury critical details in dense paragraphs. AI can handle them all. Regardless of the layout, the system consistently extracts denial codes, ensuring reliable results across various insurers. This reduces errors and prevents staff from being slowed down by unfamiliar formats.
4. Actionability
AI goes beyond identifying denial codes; it makes the next steps obvious. Whether it’s resubmitting a corrected claim, fixing a code, attaching missing paperwork, or updating insurance details, the system ensures your team can respond immediately. This reduces delays, prevents missed appeal deadlines, and speeds up reimbursement.
5. Scalability
Human teams can get overwhelmed when claim volumes spike. AI doesn’t. Whether you’re processing a few dozen EOBs or thousands, it works at the same speed and accuracy. That means no scrambling for extra staff or overtime; AI handles the workload seamlessly, scaling with your organization’s needs.
By combining speed, clarity, consistency, actionability, and scalability, AI-powered denial code decoding not only streamlines claims management but also reshapes the entire process. The result is faster resolutions, fewer errors, and healthier revenue cycles.

The Challenges of Manual Denial Code Management
Many healthcare teams still rely on manual processes to manage denial codes, but the drawbacks are becoming harder to ignore.
Delayed Payments: When denial codes must be located and interpreted by hand, claim rework slows down. Every delay in fixing and resubmitting claims directly impacts payment timelines, creating unnecessary cash flow gaps.
Dependence on Experts: Teams often rely on a small number of experienced staff members who are familiar with the intricacies of denial management. However, when these individuals are unavailable or leave the organization, work stalls, errors increase, and backlogs accumulate.
Scattered Knowledge: In many billing departments, denial handling isn’t standardized. Processes live in spreadsheets, emails, or even someone’s memory. This lack of centralized knowledge leads to inconsistent outcomes, confusion, and costly mistakes, mainly when staff turnover occurs.
Challenging Onboarding: For new hires, learning to navigate complex denial codes and payer-specific regulations can be overwhelming. It may take weeks to get up to speed, which slows productivity and leaves teams vulnerable during staffing transitions.
Error-Prone Processes: Manual interpretation increases the risk of resubmitting claims incorrectly. This leads to repeated rejections, wasted time, and unnecessary work, which is frustrating for both teams and patients.
The bottom line? Relying on manual denial management forces teams to work harder for slower results. It drains resources, frustrates staff, and disrupts cash flow. Without AI to standardize and streamline denial decoding, inefficiency becomes the norm, leading to burnout, delayed payments, and financial risk.
Final Thoughts
Denial codes may seem insignificant, but in healthcare billing, they carry significant weight. They explain why claims are rejected and what needs to be fixed. Handling them manually only slows payments and adds stress.
This is precisely where AI steps in.
AI instantly extracts and decodes denial codes from EOBs, eliminating the need to flip through code lists or visit payer sites. Your team gets clear answers quickly, acts promptly, and avoids costly errors. The result? Faster resolutions, fewer rejections, and a smoother path to payment.
Don’t let your team stay stuck in manual mode. Let AI handle the repetitive work, so your staff can focus on what matters most: getting claims paid and improving patient care.
Say goodbye to the manual grind and let AI handle denials in seconds. Contact us today to see how AI simplifies your EOB workflow.
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Navin Kumar Parthiban is a seasoned professional in the field of AI technologies and is a Director at iTech India. With a passion for innovation and a keen understanding of the ever-evolving landscape of artificial intelligence, Navin has played a pivotal role in driving iTech India’s success and technological advancements. Navin regularly shares his insights and knowledge through articles, seminars, and workshops. He believes in the power of AI to revolutionize industries and improve people’s lives, and he is dedicated to staying at the forefront of this rapidly evolving field.